When a synthetic collagen stimulator is injected under the skin, white blood cells are encouraged to surround the poly-L-lactic acid (PLLA). This triggers the release of TGF-beta and PDGF in the area, stimulating new collagen production. PLLA is slowly and naturally broken down, continuing to revitalize Type-1 collagen stores and restore skin volume. By addressing the underlying cause of skin aging, Sculptra leads to a dramatic yet natural improvement in skin texture. Unlike other procedures that stimulate collagen production, Sculptra’s effectiveness lies in its specific targeting of Type-1 collagen, the most abundant type found in the body, present in skin and tendons.